Oncologic Management of Hereditary Colorectal Cancer
نویسندگان
چکیده
منابع مشابه
Surgical management of hereditary colorectal cancer: surgery
The importance of colorectal cancer (CRC) is increasing. A proportion show a hereditary component, as in Lynch syndrome and Familial Adenomatous Polyposis, and a recently defined entity as well, namely, Familial Colorectal Cancer type X. The high probability to develop CRC in these groups may, at the time of recognition, change surgical management, including its timing or even the surgical tech...
متن کاملHereditary colorectal cancer.
The question, "Is cancer hereditary?" has been answered beyond any doubt through the discovery of germ-line cancer-causing mutations in a subset of colorectal cancers (CRCs). Clearly, this authentication of the role of genetics was not solely dependent on molecular genetic studies, since hereditary cancer syndromes such as familial adenomatous polyposis (FAP) had been known for at least 100 yea...
متن کاملHereditary nonpolyposis colorectal cancer.
Hereditary nonpolyposis colorectal cancer (HNPCC), or Lynch syndrome, is the most common form of hereditary colorectal cancer (CRC). A well-orchestrated cancer family history is essential for its diagnosis since, unlike its familial adenomatous polyposis (FAP) hereditary cancer counterpart, HNPCC lacks distinguishing clinical stigmata of its cancer genetic risk. Discoveries in the 1990s of germ...
متن کاملManagement of Patients with Hereditary Colorectal Cancer Syndromes
Colorectal cancer (CRC) is one of the most important causes of death in the world. Hereditary CRC is found in 5-10% of CRC patients. In this review, we will focus on the major forms of hereditary CRC and their management according to the most recent literature available.
متن کاملRecognition and management of hereditary colorectal cancer syndromes.
Over 1,900 colorectal tumors will arise in association with a hereditary colorectal cancer syndrome in Spain in 2009. The genetic defects responsible for the most common syndromes have been discovered in recent years. Genetic testing helps diagnose affected individuals and allows identification of individuals at-risk. Colonoscopy and prophylactic colectomy decrease colorectal cancer incidence a...
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ژورنال
عنوان ژورنال: Clinics in Colon and Rectal Surgery
سال: 2012
ISSN: 1531-0043,1530-9681
DOI: 10.1055/s-0032-1313783